A strong, stable, and comprehensive social safety-net is critical to the well-being of low-income and working families. Strong partnerships not only improve the quantity of services delivered, but also contribute to the overall quality of available services that families rely on in order to become economically self-sufficient. The Administration for Children and Families, Office of Family Assistance, Regions I, II, and III hosted the 2012 East Coast Strategic Collaborations Workshop in Philadelphia, Pennsylvania on September 18-20, 2012 in an effort to bring together TANF, workforce, child support, responsible fatherhood, housing, and community services stakeholders to map out a plan for better communication and collaboration. The workshop included targeted discussions with policy, research, and service delivery experts and culminated with an interactive building of a self-sufficiency puzzle made up of specific next steps, action items, and technical assistance needs. The workshop brought together State TANF directors, local Workforce Investment Board (WIB) directors, and other human service administrators and leaders to strategize on ways to better coordinate services for low-income and working families while improving program performance and service delivery outcomes. Workshop topics included the role of TANF in the safety-net, the current and future research agenda, career pathways, subsidized employment, and partnership development.